Neuron encodes and transmits information through generating sequences of output spikes, which is a high energy-consuming process.The spike is initiated when membrane depolarization reaches a threshold voltage.In many neurons, threshold is dynamic and depends on the rate of membrane depolarization (dV/dt) preceding a spike.Identifying the metabolic
Emerging Biomarker-Guided Therapies in Prostate Cancer
Prostate cancer remains one of the leading causes of cancer death in men worldwide.In the past decade, several new treatments for advanced prostate cancer have been approved.With a wide variety of available drugs, including cytotoxic agents, androgen receptor axis-targeted therapies, and alpha-emitting radiation therapy, identifying their optimal s
Surface-based GPU-friendly geometry modeling for detector simulation
In a context where the high-energy physics community strives to enhance software to handle increased data throughput, detector simulation is evolving to take advantage of new performance opportunities.Given the intricacy of particle transport simulation, recent advancements, such as adapting to accelerator hardware, require a significant research a
Exploration and Practice of Annual Safety Report Regulation for Long-Distance Water Diversion Projects
Long-distance water diversion projects are important strategic infrastructure to optimize the patterns of water resource allocation,which are characterized by long distances,many hydraulic structures,complex geological and environmental conditions,and high maintenance requirements.The long-term safe operation of these projects has been highly conce